Development of an advanced MES for the simulation and optimization of industry 4.0 processKhaled Benfriha, Chawki El-Zant, Quentin Charrier, Abdel-Hakim Bouzid, Peter Wardle, Idir Belaidi, Stéphane Loubère, Nooshin Ghodsian and Améziane AoussatInt. J. Simul. Multidisci. Des. Optim., 12 (2021) 23DOI: https://doi.org/10.1051/smdo/2021022